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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 426 African American or Afro-Caribbean cases, 120,593 African American or Afro-Caribbean controls, 927 European ancestry cases, 448,404 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 1.95 lower (95% confidence interval 1.89-2.02); p = 3 × 10−11.
How common The T allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 5, band 5q35.2 — inside NSG2.
What each result means
C/CNo copy of the version the research linked to Cachexia (PheCode 260.1). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Cachexia (PheCode 260.1). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cachexia (PheCode 260.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs577897177
What is rs577897177?
rs577897177 is a single position in the genome, in or near the NSG2 gene. Published research associates it with cachexia (phecode 260.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs577897177 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs577897177 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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