0 927Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others7Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 44 European ancestry cases, 350,228 European ancestry controls, 58 East Asian ancestry cases, 175,599 East Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 69 higher (95% confidence interval 45.7-92.23); p = 6 × 10−9.
Where it sits Chromosome 11, band 11q13.2 — in an intron of LRP5.
What each result means
C/CNo copy of the version the research linked to Polymyositis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Polymyositis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Polymyositis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs577482058 is a single position in the genome, in or near the LRP5 gene. Published research associates it with polymyositis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs577482058 linked to?
On MyGeneLog this position is linked to Myositis. The research behind each link, and its sources, are set out on that condition page.
Does having rs577482058 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs577482058 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 927Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others7Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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