0 127212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot7Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others2Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 30,156 European ancestry cases, 1,527,568 European ancestry controls.
The effect
Each copy of the G allele carried 1.08 times the odds of Bladder cancer (95% confidence interval 1.05429227603199-1.10377234065617); p = 1 × 10−10.
How common The G allele had a frequency of about 18% in the people studied.
Where it sits Chromosome 5, band 5q31.2 — in an intron of NRG2.
What each result means
A/ANo copy of the version the research linked to Bladder cancer. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Bladder cancer. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Bladder cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2026 · PMID 42706231 · open access
Questions about rs57742781
What is rs57742781?
rs57742781 is a single position in the genome, in or near the NRG2 gene. Published research associates it with bladder cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs57742781 linked to?
On MyGeneLog this position is linked to Bladder Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs57742781 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs57742781 come from?
GWAS Catalog, Nature communications 2026, PMID:42706231. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 127212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot7Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others2Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Bladder cancer (rs57742781). MyGeneLog™. https://www.mygenelog.com/variants/rs57742781