Sensitive

Crohn's disease

RBMS2 · rs576910164

Where this position leads

Condition: Crohn's Disease

rs576910164 Condition: Crohn's Disease Crohn's Disease Condition rs576910164 rs576910164 RBMS2

What the study found

Who was studied 311 African American or Afro-Caribbean cases, 55,194 African American or Afro-Caribbean controls, 2,256 European ancestry cases, 313,412 European ancestry controls.

The effect Each copy of the G allele shifted the measure 3.4 lower (95% confidence interval 3.38-3.42); p = 3 × 10−15.

How common The G allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 12, band 12q13.3 — in an intron of RBMS2.

What each result means

A/A No copy of the version the research linked to Crohn's disease. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Crohn's disease. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Crohn's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs576910164

What is rs576910164?

rs576910164 is a single position in the genome, in or near the RBMS2 gene. Published research associates it with crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs576910164 linked to?

On MyGeneLog this position is linked to Crohn's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs576910164 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs576910164 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Crohn's disease (rs576910164). MyGeneLog™. https://www.mygenelog.com/variants/rs576910164

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