A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Multiple sclerosis compared to the general population. (GWAS Catalog, Science 2019, PMID:31604244)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Multiple sclerosis. (GWAS Catalog, Science 2019, PMID:31604244)
G/GPublished research associates this genotype with typical/baseline likelihood of Multiple sclerosis — no copies of the reported risk allele. (GWAS Catalog, Science 2019, PMID:31604244)
rs5756405 is a single position in the genome, in or near the CSF2RB gene. Published research associates it with multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs5756405 linked to?
On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs5756405 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs5756405 come from?
GWAS Catalog, Science 2019, PMID:31604244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.