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Skin color

near RXFP3 · rs57525174

What the study found

Who was studied 4,985 Iberian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.465 lower (95% confidence interval 0.35-0.58); p = 2 × 10−14.

How common The A allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 5, band 5p13.2 — between genes, 1.8 kb from RXFP3.

What each result means

A/A Two copies of the version the research linked to Skin color. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Skin color. That is a smaller link than two copies.
G/G No copy of the version the research linked to Skin color. This is the starting point the study compared everyone against.
Source

Questions about rs57525174

What is rs57525174?

rs57525174 is a single position in the genome, in or near the near RXFP3 gene. Published research associates it with skin color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs57525174 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs57525174 come from?

GWAS Catalog, Genes 2023, PMID:36672889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Skin color (rs57525174). MyGeneLog™. https://www.mygenelog.com/variants/rs57525174

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