Standard

GLIPR1 protein levels

VSTM2B-DT · rs575159876

Where this position leads

Condition: Celiac Disease

rs575159876 Condition: Celiac Disease Celiac Disease Condition rs575159876 rs575159876 VSTM2B-DT

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.63 higher (95% confidence interval 0.46-0.8); p = 4 × 10−12.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 19, band 19q12 — in an intron of VSTM2B-DT.

What each result means

A/A Two copies of the version the research linked to GLIPR1 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to GLIPR1 protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to GLIPR1 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs575159876

What is rs575159876?

rs575159876 is a single position in the genome, in or near the VSTM2B-DT gene. Published research associates it with glipr1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs575159876 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs575159876 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs575159876 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

GLIPR1 protein levels (rs575159876). MyGeneLog™. https://www.mygenelog.com/variants/rs575159876

← See all variants