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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 327,790 British ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.022 lower (95% confidence interval 0.014-0.03); p = 5 × 10−8.
How common The C allele had a frequency of about 9% in the people studied.
Where it sits Chromosome 22, band 22q11.1 — in an intron of GAB4.
What each result means
C/CTwo copies of the version the research linked to Leukocyte telomere length. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Leukocyte telomere length. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Leukocyte telomere length. This is the starting point the study compared everyone against.
rs5748769 is a single position in the genome, in or near the GAB4 gene. Published research associates it with leukocyte telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs5748769 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs5748769 come from?
GWAS Catalog, GeroScience 2024, PMID:38837026. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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