Standard

Telomere length (principal component 1)

RBM25 · rs574806782

What the study found

Who was studied 438,351 Non-Finnish European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0741 lower (95% confidence interval 0.063-0.085); p = 3 × 10−38.

Where it sits Chromosome 14, band 14q24.2 — in an intron of RBM25.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Telomere length (principal component 1) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Telomere length (principal component 1).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Telomere length (principal component 1) compared to the general population.
Source

Questions about rs574806782

What is rs574806782?

rs574806782 is a single position in the genome, in or near the RBM25 gene. Published research associates it with telomere length (principal component 1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs574806782 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs574806782 come from?

GWAS Catalog, Nature genetics 2024, PMID:39192095. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Telomere length (principal component 1) (rs574806782). MyGeneLog™. https://www.mygenelog.com/variants/rs574806782

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