Sensitive

Tumor necrosis factor receptor superfamily member 1B levels

TNFRSF1B · rs5746011

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.442 higher (95% confidence interval 0.38-0.51); p = 4 × 10−38.

How common The T allele had a frequency of about 96% in the people studied.

Where it sits Chromosome 1, band 1p36.22 — in an intron of TNFRSF1B.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Tumor necrosis factor receptor superfamily member 1B levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Tumor necrosis factor receptor superfamily member 1B levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Tumor necrosis factor receptor superfamily member 1B levels compared to the general population.
Source

Questions about rs5746011

What is rs5746011?

rs5746011 is a single position in the genome, in or near the TNFRSF1B gene. Published research associates it with tumor necrosis factor receptor superfamily member 1b levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs5746011 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs5746011 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Tumor necrosis factor receptor superfamily member 1B levels (rs5746011). MyGeneLog™. https://www.mygenelog.com/variants/rs5746011

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