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Lipopolysaccharide-binding protein levels

LBP · rs5744204

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.941 lower (95% confidence interval 0.87-1.01); p = 4 × 10⁻¹⁴².

How common The A allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 20, band 20q11.23 — a missense change in LBP.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lipopolysaccharide-binding protein levels compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lipopolysaccharide-binding protein levels.

G/G Published research associates this genotype with typical/baseline likelihood of Lipopolysaccharide-binding protein levels — no copies of the reported risk allele.

Source

Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations

Thareja G, Belkadi A, Arnold M, Albagha OME, Graumann J, Schmidt F, Grallert H, Peters A, Gieger C, Consortium TQGPR, Suhre K

Human molecular genetics · 2023 · PMID 36168886 · open access

Questions about rs5744204

What is rs5744204?

rs5744204 is a single position in the genome, in or near the LBP gene. Published research associates it with lipopolysaccharide-binding protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs5744204 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs5744204 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lipopolysaccharide-binding protein levels (rs5744204). MyGeneLog™. https://www.mygenelog.com/variants/rs5744204

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