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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied up to 100,285 Chinese ancestry individuals; replicated in up to 457,756 European ancestry individuals.
The effect
The reported allele is C; the catalogue records no effect size
; p = 2 × 10−11.
Where it sits Chromosome 12, band 12q23.2 — in an intron of LINC02456.
What each result means
C/CTwo copies of the version the research linked to Lung function (FEV1) and body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Lung function (FEV1) and body mass index. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Lung function (FEV1) and body mass index. This is the starting point the study compared everyone against.
The European respiratory journal · 2021 · PMID 33766948
Questions about rs5742653
What is rs5742653?
rs5742653 is a single position in the genome, in or near the LINC02456 gene. Published research associates it with lung function (fev1) and body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs5742653 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs5742653 come from?
GWAS Catalog, The European respiratory journal 2021, PMID:33766948. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Lung function (FEV1) and body mass index (rs5742653). MyGeneLog™. https://www.mygenelog.com/variants/rs5742653