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Infantile hypertrophic pyloric stenosis

LINC02006 · rs573872

Where this position leads

Condition: Infantile Hypertrophic Pyloric Stenosis

rs573872 Condition: Infantile Hypertrophic Pyloric Stenosis Infantile Hypertrophic Pyloric Stenosis Condition rs573872 rs573872 LINC02006

What the study found

Who was studied 1,395 Danish ancestry cases, 4,438 Danish ancestry controls; replicated in 1,794 European ancestry cases, 633 Hispanic ancestry cases, 1,875 European ancestry controls, 633 Hispanic ancestry controls.

The effect Each copy of the G allele carried 1.32 times the odds of Infantile hypertrophic pyloric stenosis (95% confidence interval 1.25-1.38); p = 2 × 10−15.

How common The G allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 3, band 3q25.2 — in an intron of LINC02006.

What each result means

G/G Two copies of the version the research linked to Infantile hypertrophic pyloric stenosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Infantile hypertrophic pyloric stenosis. That is a smaller link than two copies.
T/T No copy of the version the research linked to Infantile hypertrophic pyloric stenosis. This is the starting point the study compared everyone against.
Source

Questions about rs573872

What is rs573872?

rs573872 is a single position in the genome, in or near the LINC02006 gene. Published research associates it with infantile hypertrophic pyloric stenosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs573872 linked to?

On MyGeneLog this position is linked to Infantile Hypertrophic Pyloric Stenosis. The research behind each link, and its sources, are set out on that condition page.

Does having rs573872 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs573872 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:30281099. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Infantile hypertrophic pyloric stenosis (rs573872). MyGeneLog™. https://www.mygenelog.com/variants/rs573872

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