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Who was studied 12,019 European ancestry cases, 1,869,646 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 2.02 higher (95% confidence interval 1.42-2.62); p = 4 × 10−11.
How common The C allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 8, band 8q12.1 — in an intron of RP1.
What each result means
C/CTwo copies of the version the research linked to Graves' disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Graves' disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Graves' disease. This is the starting point the study compared everyone against.
Nature genetics · 2026 · PMID 41644669 · open access
Questions about rs573463009
What is rs573463009?
rs573463009 is a single position in the genome, in or near the RP1 gene. Published research associates it with graves' disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs573463009 linked to?
On MyGeneLog this position is linked to Graves' Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs573463009 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs573463009 come from?
GWAS Catalog, Nature genetics 2026, PMID:41644669. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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