0 151239Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3Others9Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.055 higher; p = 1 × 10−8.
Where it sits Chromosome 10, band 10q22.1 — in an intron of OIT3.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Low density lipoprotein cholesterol levels — no copies of the reported risk allele.
A/CPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Low density lipoprotein cholesterol levels.
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Low density lipoprotein cholesterol levels compared to the general population.
Nature genetics · 2018 · PMID 29507422 · open access
Questions about rs57176252
What is rs57176252?
rs57176252 is a single position in the genome, in or near the OIT3 gene. Published research associates it with low density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs57176252 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs57176252 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs57176252 come from?
GWAS Catalog, Nat Genet 2018, PMID:29507422. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 151239Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3Others9Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Low density lipoprotein cholesterol levels (rs57176252). MyGeneLog™. https://www.mygenelog.com/variants/rs57176252