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Serum 25-Hydroxyvitamin D levels

COPB1 · rs571484036

What the study found

Who was studied 443,734 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.217 lower (95% confidence interval 0.16-0.27); p = 4 × 10−16.

How common The A allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 11, band 11p15.2 — in an intron of COPB1.

What each result means

A/A Two copies of the version the research linked to Serum 25-Hydroxyvitamin D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Serum 25-Hydroxyvitamin D levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum 25-Hydroxyvitamin D levels. This is the starting point the study compared everyone against.
Source

Questions about rs571484036

What is rs571484036?

rs571484036 is a single position in the genome, in or near the COPB1 gene. Published research associates it with serum 25-hydroxyvitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs571484036 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs571484036 come from?

GWAS Catalog, American journal of human genetics 2020, PMID:32059762. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum 25-Hydroxyvitamin D levels (rs571484036). MyGeneLog™. https://www.mygenelog.com/variants/rs571484036

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