Standard

Dihomo-gamma-linolenic acid levels

LINGO1 · rs57112407

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 1,454 Hispanic or Latin American individuals.

The effect Each copy of the T allele shifted the measure 5.86 z score lower; p = 4 × 10⁻⁹.

How common The T allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 15, band 15q24.3 — inside LINGO1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Dihomo-gamma-linolenic acid levels — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Dihomo-gamma-linolenic acid levels.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Dihomo-gamma-linolenic acid levels compared to the general population.

Source

Genome-wide association studies and fine-mapping identify genomic loci for n-3 and n-6 polyunsaturated fatty acids in Hispanic American and African American cohorts

Yang C, Veenstra J, Bartz TM, Pahl MC, Hallmark B, Chen YI, Westra J, Steffen LM, Brown CD, Siscovick D, Tsai MY, Wood AC

and 9 more — show all

Rich SS, Smith CE, O'Connor TD, Mozaffarian D, Grant SFA, Chilton FH, Tintle NL, Lemaitre RN, Manichaikul A

Communications biology · 2023 · PMID 37587153 · open access

Questions about rs57112407

What is rs57112407?

rs57112407 is a single position in the genome, in or near the LINGO1 gene. Published research associates it with dihomo-gamma-linolenic acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs57112407 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs57112407 come from?

GWAS Catalog, Communications biology 2023, PMID:37587153. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Dihomo-gamma-linolenic acid levels (rs57112407). MyGeneLog™. https://www.mygenelog.com/variants/rs57112407

← See all variants