Standard

EGFL7 protein levels

FUT10 · rs570705264

Where this position leads

Condition: Celiac Disease

rs570705264 Condition: Celiac Disease Celiac Disease Condition rs570705264 rs570705264 FUT10

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.318 lower (95% confidence interval 0.23-0.41); p = 6 × 10−13.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 8, band 8p12 — in an intron of FUT10.

What each result means

A/A Two copies of the version the research linked to EGFL7 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to EGFL7 protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to EGFL7 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs570705264

What is rs570705264?

rs570705264 is a single position in the genome, in or near the FUT10 gene. Published research associates it with egfl7 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs570705264 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs570705264 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs570705264 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

EGFL7 protein levels (rs570705264). MyGeneLog™. https://www.mygenelog.com/variants/rs570705264

← See all variants