Standard

Mitochondrial DNA copy number

TWNK · rs57066921

What the study found

Who was studied 395,718 British, Irish, Other White, South Asian, African ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.108 lower (95% confidence interval 0.092-0.124); p = 9 × 10−41.

How common The G allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 10, band 10q24.31 — in an intron of TWNK.

What each result means

G/G Two copies of the version the research linked to Mitochondrial DNA copy number. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Mitochondrial DNA copy number. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mitochondrial DNA copy number. This is the starting point the study compared everyone against.
Source

Questions about rs57066921

What is rs57066921?

rs57066921 is a single position in the genome, in or near the TWNK gene. Published research associates it with mitochondrial dna copy number. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs57066921 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs57066921 come from?

GWAS Catalog, eLife 2022, PMID:35023831. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Mitochondrial DNA copy number (rs57066921). MyGeneLog™. https://www.mygenelog.com/variants/rs57066921

← See all variants