Sensitive

Colorectal cancer

SLCO2A1 · rs57064586

Where this position leads

Condition: Colorectal Cancer

rs57064586 Condition: Colorectal Cancer Colorectal Cancer Condition rs57064586 rs57064586 SLCO2A1

What the study found

Who was studied 6,581 European ancestry cases, 463,421 European ancestry controls, 8,305 East Asian ancestry cases, 159,386 East Asian ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0965 lower (95% confidence interval 0.067-0.126); p = 3 × 10−10.

Where it sits Chromosome 3, band 3q22.2 — in an intron of SLCO2A1.

What each result means

A/A No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs57064586

What is rs57064586?

rs57064586 is a single position in the genome, in or near the SLCO2A1 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs57064586 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs57064586 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs57064586 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs57064586). MyGeneLog™. https://www.mygenelog.com/variants/rs57064586

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