Sensitive

Mean platelet thrombocyte volume (UKB data field 30100)

VAMP4 · rs570382952

Where this position leads

Condition: Celiac Disease

rs570382952 Condition: Celiac Disease Celiac Disease Condition rs570382952 rs570382952 VAMP4

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0899 higher (95% confidence interval 0.063-0.117); p = 5 × 10−12.

How common The G allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 1, band 1q24.3 — in an intron of VAMP4.

What each result means

A/A No copy of the version the research linked to Mean platelet thrombocyte volume (UKB data field 30100). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Mean platelet thrombocyte volume (UKB data field 30100). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Mean platelet thrombocyte volume (UKB data field 30100). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs570382952

What is rs570382952?

rs570382952 is a single position in the genome, in or near the VAMP4 gene. Published research associates it with mean platelet thrombocyte volume (ukb data field 30100). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs570382952 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs570382952 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs570382952 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean platelet thrombocyte volume (UKB data field 30100) (rs570382952). MyGeneLog™. https://www.mygenelog.com/variants/rs570382952

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