Sensitive

Polycystic ovary syndrome in overweight/obese individuals (BMI > 25 kg/m2)

DENND1A · rs569675099

Where this position leads

Condition: Polycystic Ovary Syndrome

rs569675099 Condition: Polycystic Ovary Syndrome Polycystic Ovary Syndrome Condition rs569675099 rs569675099 DENND1A

What the study found

Who was studied 3,018 European ancestry female cases, 131,986 European ancestry female controls.

The effect Each copy of the A allele shifted the measure 0.85 higher; p = 3 × 10−9.

Where it sits Chromosome 9, band 9q33.3 — in an intron of DENND1A.

What each result means

A/A Two copies of the version the research linked to Polycystic ovary syndrome in overweight/obese individuals (BMI > 25 kg/m2). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Polycystic ovary syndrome in overweight/obese individuals (BMI > 25 kg/m2). That is a smaller link than two copies.
G/G No copy of the version the research linked to Polycystic ovary syndrome in overweight/obese individuals (BMI > 25 kg/m2). This is the starting point the study compared everyone against.
Source

Questions about rs569675099

What is rs569675099?

rs569675099 is a single position in the genome, in or near the DENND1A gene. Published research associates it with polycystic ovary syndrome in overweight/obese individuals (bmi > 25 kg/m2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs569675099 linked to?

On MyGeneLog this position is linked to Polycystic Ovary Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs569675099 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs569675099 come from?

GWAS Catalog, BMC genomics 2024, PMID:38408933. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Polycystic ovary syndrome in overweight/obese individuals (BMI > 25 kg/m2) (rs569675099). MyGeneLog™. https://www.mygenelog.com/variants/rs569675099

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