Sensitive

Systemic lupus erythematosus (PheCode 695.42)

DCDC1 · rs569133224

Where this position leads

Condition: Systemic Lupus Erythematosus

rs569133224 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs569133224 rs569133224 DCDC1

What the study found

Who was studied 740 African American or Afro-Caribbean cases, 120,993 African American or Afro-Caribbean controls, 1,013 European ancestry cases, 449,940 European ancestry controls, 212 Hispanic or Latin American cases, 59,641 Hispanic or Latin American controls.

The effect Each copy of the T allele shifted the measure 3.51 lower (95% confidence interval 3.49-3.53); p = 1 × 10−11.

How common The T allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 11, band 11p14.1 — in an intron of DCDC1.

What each result means

A/A No copy of the version the research linked to Systemic lupus erythematosus (PheCode 695.42). This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Systemic lupus erythematosus (PheCode 695.42). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systemic lupus erythematosus (PheCode 695.42). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs569133224

What is rs569133224?

rs569133224 is a single position in the genome, in or near the DCDC1 gene. Published research associates it with systemic lupus erythematosus (phecode 695.42). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs569133224 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

Does having rs569133224 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs569133224 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systemic lupus erythematosus (PheCode 695.42) (rs569133224). MyGeneLog™. https://www.mygenelog.com/variants/rs569133224

← See all variants