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TOR1AIP1 protein levels

TDRD5 · rs569068618

Where this position leads

Condition: Celiac Disease

rs569068618 Condition: Celiac Disease Celiac Disease Condition rs569068618 rs569068618 TDRD5

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.321 lower (95% confidence interval 0.22-0.42); p = 3 × 10−12.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 1, band 1q25.2 — in an intron of TDRD5.

What each result means

G/G No copy of the version the research linked to TOR1AIP1 protein levels. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to TOR1AIP1 protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to TOR1AIP1 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs569068618

What is rs569068618?

rs569068618 is a single position in the genome, in or near the TDRD5 gene. Published research associates it with tor1aip1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs569068618 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs569068618 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs569068618 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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TOR1AIP1 protein levels (rs569068618). MyGeneLog™. https://www.mygenelog.com/variants/rs569068618

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