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CLSTN2 protein levels

CLSTN2 · rs566028903

Where this position leads

Condition: Celiac Disease

rs566028903 Condition: Celiac Disease Celiac Disease Condition rs566028903 rs566028903 CLSTN2

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.363 lower (95% confidence interval 0.25-0.47); p = 4 × 10−12.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 3, band 3q23 — in an intron of CLSTN2.

What each result means

A/A Two copies of the version the research linked to CLSTN2 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to CLSTN2 protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to CLSTN2 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs566028903

What is rs566028903?

rs566028903 is a single position in the genome, in or near the CLSTN2 gene. Published research associates it with clstn2 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs566028903 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs566028903 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs566028903 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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CLSTN2 protein levels (rs566028903). MyGeneLog™. https://www.mygenelog.com/variants/rs566028903

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