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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 443,734 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.308 higher (95% confidence interval 0.22-0.4); p = 7 × 10−11.
How common The T allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 4, band 4q13.3 — in an intron of GC.
What each result means
G/GNo copy of the version the research linked to Serum 25-Hydroxyvitamin D levels. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Serum 25-Hydroxyvitamin D levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Serum 25-Hydroxyvitamin D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2020 · PMID 32059762
Questions about rs565277381
What is rs565277381?
rs565277381 is a single position in the genome, in or near the GC gene. Published research associates it with serum 25-hydroxyvitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs565277381 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs565277381 come from?
GWAS Catalog, American journal of human genetics 2020, PMID:32059762. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Serum 25-Hydroxyvitamin D levels (rs565277381). MyGeneLog™. https://www.mygenelog.com/variants/rs565277381