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Prothrombin time

near F10 · rs563964

What the study found

Who was studied 4,505 Korean ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0202 lower; p = 7 × 10−30.

How common The C allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 13, band 13q34 — between genes, 0.2 kb from F10.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-11-11. ClinVar record 1261160 NC_000013.11:g.113122633T>C

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

C/C Two copies of the version the research linked to Prothrombin time. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Prothrombin time. That is a smaller link than two copies.
T/T No copy of the version the research linked to Prothrombin time. This is the starting point the study compared everyone against.
Source

Questions about rs563964

What is rs563964?

rs563964 is a single position in the genome, in or near the near F10 gene. Published research associates it with prothrombin time. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs563964 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs563964 come from?

GWAS Catalog, Scientific reports 2022, PMID:35121771. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prothrombin time (rs563964). MyGeneLog™. https://www.mygenelog.com/variants/rs563964

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