0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 43,639 European ancestry cases, 506,798 European ancestry controls; replicated in 1,089 cases, 5,228 controls.
The effect
Each copy of the C allele carried 0.92 times the odds of Gallstone disease (95% confidence interval 0.9-0.93); p = 2 × 10−11.
Where it sits Chromosome 6, band 6q16.3 — in an intron of LIN28B.
What each result means
A/ANo copy of the version the research linked to Gallstone disease. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Gallstone disease. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Gallstone disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs56339318 is a single position in the genome, in or near the LIN28B gene. Published research associates it with gallstone disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs56339318 linked to?
On MyGeneLog this position is linked to Gallstone Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs56339318 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs56339318 come from?
GWAS Catalog, Hepatology (Baltimore, Md.) 2022, PMID:34651315. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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