Sensitive

Attention deficit hyperactivity disorder or cannabis use

KDM4A-AS1 · rs56319043

Where this position leads

Condition: ADHD (Attention Deficit Hyperactivity Disorder)

rs56319043 Condition: ADHD (Attention Deficit Hyperactivity Disorder) ADHD (Attention Deficit Hyperactivi… Condition rs56319043 rs56319043 KDM4A-AS1

What the study found

Who was studied 18,345 European ancestry ADHD cases, 14,374 European ancestry cannabis use cases, 50,410 European ancestry controls.

The effect Each copy of the C allele carried 1.09 times the odds of Attention deficit hyperactivity disorder or cannabis use (95% confidence interval 1.05-1.11); p = 4 × 10−9.

Where it sits Chromosome 1, band 1p34.1 — in an intron of KDM4A-AS1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Attention deficit hyperactivity disorder or cannabis use compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Attention deficit hyperactivity disorder or cannabis use.
T/T Published research associates this genotype with typical/baseline likelihood of Attention deficit hyperactivity disorder or cannabis use — no copies of the reported risk allele.
Source

Questions about rs56319043

What is rs56319043?

rs56319043 is a single position in the genome, in or near the KDM4A-AS1 gene. Published research associates it with attention deficit hyperactivity disorder or cannabis use. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs56319043 linked to?

On MyGeneLog this position is linked to ADHD (Attention Deficit Hyperactivity Disorder). The research behind each link, and its sources, are set out on that condition page.

Does having rs56319043 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56319043 come from?

GWAS Catalog, Mol Psychiatry 2019, PMID:30610198. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Attention deficit hyperactivity disorder or cannabis use (rs56319043). MyGeneLog™. https://www.mygenelog.com/variants/rs56319043

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