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Insomnia

KCNIP4 · rs56318309

Where this position leads

Condition: Insomnia

rs56318309 Condition: Insomnia Insomnia Condition rs56318309 rs56318309 KCNIP4

What the study found

Who was studied 593,724 European ancestry cases, 1,771,286 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.007 higher (95% confidence interval 0.005-0.009); p = 3 × 10−10.

Where it sits Chromosome 4, band 4p15.2 — in an intron of KCNIP4.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Insomnia compared to the general population.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Insomnia.
T/T Published research associates this genotype with typical/baseline likelihood of Insomnia — no copies of the reported risk allele.
Source

Questions about rs56318309

What is rs56318309?

rs56318309 is a single position in the genome, in or near the KCNIP4 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs56318309 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs56318309 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56318309 come from?

GWAS Catalog, Nature genetics 2022, PMID:35835914. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs56318309). MyGeneLog™. https://www.mygenelog.com/variants/rs56318309

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