Standard

Medication use (agents acting on the renin-angiotensin system)

ZCCHC7 · rs563132

Where this position leads

Condition: Medication Use as a Genetic Trait

rs563132 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs563132 rs563132 ZCCHC7

What the study found

Who was studied 62,752 European ancestry cases, 174,778 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0339 lower (95% confidence interval 0.022-0.046); p = 4 × 10−8.

How common The T allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 9, band 9p13.2 — in an intron of ZCCHC7.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Medication use (agents acting on the renin-angiotensin system) — no copies of the reported risk allele.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (agents acting on the renin-angiotensin system).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (agents acting on the renin-angiotensin system) compared to the general population.
Source

Questions about rs563132

What is rs563132?

rs563132 is a single position in the genome, in or near the ZCCHC7 gene. Published research associates it with medication use (agents acting on the renin-angiotensin system). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs563132 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs563132 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs563132 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Medication use (agents acting on the renin-angiotensin system) (rs563132). MyGeneLog™. https://www.mygenelog.com/variants/rs563132

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