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Atrial fibrillation

EEFSEC · rs56287882

Where this position leads

Condition: Atrial Fibrillation

rs56287882 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs56287882 rs56287882 EEFSEC

What the study found

Who was studied 228,926 European ancestry cases, 1,611,415 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.034 lower (95% confidence interval 0.023-0.045); p = 1 × 10−9.

How common The A allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 3, band 3q21.3 — in an intron of EEFSEC.

What each result means

A/A Two copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
G/G No copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
Source

Questions about rs56287882

What is rs56287882?

rs56287882 is a single position in the genome, in or near the EEFSEC gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs56287882 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs56287882 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56287882 come from?

GWAS Catalog, Nature communications 2025, PMID:40645996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (rs56287882). MyGeneLog™. https://www.mygenelog.com/variants/rs56287882

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