Standard

High myopia

PDE6G · rs562698611

Where this position leads

Condition: Myopia

rs562698611 Condition: Myopia Myopia Condition rs562698611 rs562698611 PDE6G

What the study found

Who was studied 2,737 British ancestry cases, 47,635 British ancestry controls.

The effect Each copy of the G allele carried 1.23 times the odds of High myopia (95% confidence interval 1.161475-1.299783); p = 2 × 10−13.

How common The G allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 17, band 17q25.3 — inside PDE6G.

What each result means

A/A No copy of the version the research linked to High myopia. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to High myopia. That is a smaller link than two copies.
G/G Two copies of the version the research linked to High myopia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs562698611

What is rs562698611?

rs562698611 is a single position in the genome, in or near the PDE6G gene. Published research associates it with high myopia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs562698611 linked to?

On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.

Does having rs562698611 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs562698611 come from?

GWAS Catalog, Human molecular genetics 2020, PMID:31816047. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

High myopia (rs562698611). MyGeneLog™. https://www.mygenelog.com/variants/rs562698611

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