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Linoleic acid levels

CYP2A6 · rs56267346

Where this position leads

Drug: Smoking cessation medicines

rs56267346 Drug: Smoking cessation medicines Smoking cessation medicines Drug rs56267346 rs56267346 CYP2A6

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 2 × 10−10.

Where it sits Chromosome 19, band 19q13.2 — in an intron of CYP2A6.

What each result means

A/A No copy of the version the research linked to Linoleic acid levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Linoleic acid levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Linoleic acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs56267346

What is rs56267346?

rs56267346 is a single position in the genome, in or near the CYP2A6 gene. Published research associates it with linoleic acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs56267346 affect how medicines work?

CYP2A6 carries pharmacogenomic findings for Smoking cessation medicines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs56267346 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56267346 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Linoleic acid levels (rs56267346). MyGeneLog™. https://www.mygenelog.com/variants/rs56267346

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