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Who was studied 394,642 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0372 lower (95% confidence interval 0.031-0.043); p = 9 × 10−35.
How common The T allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 19, band 19q13.31 — in an intron of CEACAM16-AS1.
What each result means
C/CNo copy of the version the research linked to C-reactive protein levels (UKB data field 30710). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to C-reactive protein levels (UKB data field 30710). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to C-reactive protein levels (UKB data field 30710). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2025 · PMID 39789286 · open access
Questions about rs56261258
What is rs56261258?
rs56261258 is a single position in the genome, in or near the CEACAM16-AS1 gene. Published research associates it with c-reactive protein levels (ukb data field 30710). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs56261258 linked to?
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs56261258 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs56261258 come from?
GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
C-reactive protein levels (UKB data field 30710) (rs56261258). MyGeneLog™. https://www.mygenelog.com/variants/rs56261258