Standard

Total bilirubin levels

near CDK5RAP2 · rs562565452

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.253 lower (95% confidence interval 0.17-0.33); p = 8 × 10⁻¹⁰.

Where it sits Chromosome 9, band 9q33.2 — between genes, 69.1 kb from MIR147A.

What each result means

A/A Two copies of the version the research linked to Total bilirubin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.

A/G One copy of the version the research linked to Total bilirubin levels. That is a smaller link than two copies.

G/G No copy of the version the research linked to Total bilirubin levels. This is the starting point the study compared everyone against.

Source

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures

Jee YH, Wang Y, Jung KJ, Lee JY, Kimm H, Duan R, Price AL, Martin AR, Kraft P

Nature communications · 2025 · PMID 40436827 · open access

Questions about rs562565452

What is rs562565452?

rs562565452 is a single position in the genome, in or near the near CDK5RAP2 gene. Published research associates it with total bilirubin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs562565452 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs562565452 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total bilirubin levels (rs562565452). MyGeneLog™. https://www.mygenelog.com/variants/rs562565452

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