Standard

Sum basophil neutrophil counts

near PPP1R8 · rs56232812

Where this position leads

Condition: Blood Cell Counts

rs56232812 Condition: Blood Cell Counts Blood Cell Counts Condition rs56232812 rs56232812 near PPP1R8

What the study found

Who was studied 170,143 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0345 lower (95% confidence interval 0.023-0.046); p = 7 × 10−9.

How common The C allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 1, band 1p35.3 — between genes, 8.3 kb from PPP1R8.

What each result means

A/A No copy of the version the research linked to Sum basophil neutrophil counts. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Sum basophil neutrophil counts. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Sum basophil neutrophil counts. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs56232812

What is rs56232812?

rs56232812 is a single position in the genome, in or near the near PPP1R8 gene. Published research associates it with sum basophil neutrophil counts. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs56232812 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs56232812 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56232812 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sum basophil neutrophil counts (rs56232812). MyGeneLog™. https://www.mygenelog.com/variants/rs56232812

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