Standard

Age at menarche or uterine leiomyomata (pleiotropy)

RIC8A · rs56186913

Where this position leads

Condition: Age at Menarche

rs56186913 Condition: Age at Menarche Age at Menarche Condition rs56186913 rs56186913 RIC8A

What the study found

Who was studied 35,474 European ancestry uterine leiomyomata cases, 267,505 European ancestry controls, 329,345 European ancestry individuals with age at menarche measurements.

The effect The reported allele is T; the catalogue records no effect size ; p = 6 × 10−14.

Where it sits Chromosome 11, band 11p15.5 — in the 5′ untranslated region of RIC8A.

What each result means

C/C No copy of the version the research linked to Age at menarche or uterine leiomyomata (pleiotropy). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Age at menarche or uterine leiomyomata (pleiotropy). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Age at menarche or uterine leiomyomata (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs56186913

What is rs56186913?

rs56186913 is a single position in the genome, in or near the RIC8A gene. Published research associates it with age at menarche or uterine leiomyomata (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs56186913 linked to?

On MyGeneLog this position is linked to Age at Menarche. The research behind each link, and its sources, are set out on that condition page.

Does having rs56186913 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56186913 come from?

GWAS Catalog, American journal of obstetrics and gynecology 2024, PMID:38191017. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Age at menarche or uterine leiomyomata (pleiotropy) (rs56186913). MyGeneLog™. https://www.mygenelog.com/variants/rs56186913

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