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Who was studied 3,991 European ancestry cases, 1,105,408 European ancestry controls; replicated in 218 cases, 99,241 controls.
The effect
Each copy of the A allele carried 1.43 times the odds of Multiple myeloma (95% confidence interval 1.27-1.62); p = 1 × 10−8.
How common The A allele had a frequency of about 9% in the people studied.
Where it sits Chromosome 1, band 1q23.1 — between genes, 5.5 kb from CD5L.
What each result means
A/ATwo copies of the version the research linked to Multiple myeloma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Multiple myeloma. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Multiple myeloma. This is the starting point the study compared everyone against.
Blood cancer journal · 2025 · PMID 40883272 · open access
Questions about rs56179914
What is rs56179914?
rs56179914 is a single position in the genome, in or near the near CD5L gene. Published research associates it with multiple myeloma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs56179914 linked to?
On MyGeneLog this position is linked to Multiple Myeloma. The research behind each link, and its sources, are set out on that condition page.
Does having rs56179914 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs56179914 come from?
GWAS Catalog, Blood cancer journal 2025, PMID:40883272. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2616223111Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others11Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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