Standard

3-Hydroxybutyrate levels

ZFHX3 · rs56177707

What the study found

Who was studied 199,732 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0433 higher (95% confidence interval 0.03-0.057); p = 4 × 10−10.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 16, band 16q22.3 — in an intron of ZFHX3.

What each result means

A/A Two copies of the version the research linked to 3-Hydroxybutyrate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to 3-Hydroxybutyrate levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to 3-Hydroxybutyrate levels. This is the starting point the study compared everyone against.
Source

Questions about rs56177707

What is rs56177707?

rs56177707 is a single position in the genome, in or near the ZFHX3 gene. Published research associates it with 3-hydroxybutyrate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs56177707 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56177707 come from?

GWAS Catalog, British journal of cancer 2025, PMID:40307439. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

3-Hydroxybutyrate levels (rs56177707). MyGeneLog™. https://www.mygenelog.com/variants/rs56177707

← See all variants