AKT3 · rs560977020
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 83,677 British ancestry cases, 244,662 British ancestry controls; replicated in 2,764 South Asian ancestry cases, 3,139 African Caribbean ancestry cases, 16,169 European ancestry cases, 3,866 mixed ancestry cases, 4,267 South Asian ancestry controls, 4,341 African Caribbean ancestry controls, 31,814 European ancestry controls, 5,988 mixed ancestry controls.
The effect Each copy of the T allele shifted the measure 0.034 higher (95% confidence interval 0.024-0.044); p = 3 × 10−10.
How common The T allele had a frequency of about 66% in the people studied.
Where it sits Chromosome 1, band 1q44 — in an intron of AKT3.
rs560977020 is a single position in the genome, in or near the AKT3 gene. Published research associates it with self-reported risk-taking behaviour. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Translational psychiatry 2018, PMID:30181555. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Self-reported risk-taking behaviour (rs560977020). MyGeneLog™. https://www.mygenelog.com/variants/rs560977020