2 2022115Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others15Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 18,034 African or African American cases, 22,104 African or African American controls.
The effect
Each copy of the A allele carried 1.13 times the odds of Breast cancer (95% confidence interval 1.09-1.17); p = 1 × 10−11.
How common The A allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 19, band 19p13.11 — in an intron of ANKLE1.
What ClinVar records
ClassificationBenign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2019-01-18.
ClinVar record 1281673NM_152363.6(ANKLE1):c.461-109C>A
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Breast cancer. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Breast cancer. This is the starting point the study compared everyone against.
rs56069439 is a single position in the genome, in or near the ANKLE1 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs56069439 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs56069439 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs56069439 come from?
GWAS Catalog, Nature genetics 2024, PMID:38741014. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 2022115Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others15Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Breast cancer (rs56069439). MyGeneLog™. https://www.mygenelog.com/variants/rs56069439