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Inguinal hernia

HAND2-AS1 · rs56063997

Where this position leads

Condition: Inguinal Hernia

rs56063997 Condition: Inguinal Hernia Inguinal Hernia Condition rs56063997 rs56063997 HAND2-AS1

What the study found

Who was studied 18,791 European ancestry cases, 93,955 European ancestry controls.

The effect Each copy of the C allele carried 1.07 times the odds of Inguinal hernia (95% confidence interval 1.05-1.1); p = 4 × 10−10.

How common The C allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 4, band 4q34.1 — inside HAND2-AS1.

What each result means

C/C Two copies of the version the research linked to Inguinal hernia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Inguinal hernia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Inguinal hernia. This is the starting point the study compared everyone against.
Source

Questions about rs56063997

What is rs56063997?

rs56063997 is a single position in the genome, in or near the HAND2-AS1 gene. Published research associates it with inguinal hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs56063997 linked to?

On MyGeneLog this position is linked to Inguinal Hernia. The research behind each link, and its sources, are set out on that condition page.

Does having rs56063997 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56063997 come from?

GWAS Catalog, PloS one 2022, PMID:36584111. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Inguinal hernia (rs56063997). MyGeneLog™. https://www.mygenelog.com/variants/rs56063997

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