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Who was studied 74,152 European ancestry cases, 363,596 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.0498 higher (95% confidence interval 0.038-0.062); p = 2 × 10−20.
How common The C allele had a frequency of about 45% in the people studied.
Where it sits Chromosome 12, band 12q21.2 — between genes, 97.1 kb from RN7SL734P.
What each result means
C/CTwo copies of the version the research linked to Atrial fibrillation and flutter (PheCode 427.2). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Atrial fibrillation and flutter (PheCode 427.2). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Atrial fibrillation and flutter (PheCode 427.2). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs56059557
What is rs56059557?
rs56059557 is a single position in the genome, in or near the near RN7SL734P gene. Published research associates it with atrial fibrillation and flutter (phecode 427.2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs56059557 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs56059557 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs56059557 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 231123115Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others15Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Atrial fibrillation and flutter (PheCode 427.2) (rs56059557). MyGeneLog™. https://www.mygenelog.com/variants/rs56059557