Sensitive

Sjögren's syndrome

TSBP1-AS1 · rs56036302

Where this position leads

Condition: Sjögren's Syndrome

rs56036302 Condition: Sjögren's Syndrome Sjögren's Syndrome Condition rs56036302 rs56036302 TSBP1-AS1

What the study found

Who was studied 303 East Asian ancestry cases, 175,599 East Asian ancestry controls.

The effect Each copy of the T allele shifted the measure 0.668 higher (95% confidence interval 0.46-0.88); p = 6 × 10−10.

How common The T allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in an intron of TSBP1-AS1.

What each result means

A/A No copy of the version the research linked to Sjögren's syndrome. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Sjögren's syndrome. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Sjögren's syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs56036302

What is rs56036302?

rs56036302 is a single position in the genome, in or near the TSBP1-AS1 gene. Published research associates it with sjögren's syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs56036302 linked to?

On MyGeneLog this position is linked to Sjögren's Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs56036302 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56036302 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sjögren's syndrome (rs56036302). MyGeneLog™. https://www.mygenelog.com/variants/rs56036302

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