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Blond vs. brown/black hair color

OVOL1 · rs56019505

Where this position leads

Condition: Hair Color

rs56019505 Condition: Hair Color Hair Color Condition rs56019505 rs56019505 OVOL1

What the study found

Who was studied 39,397 British ancestry blond hair individuals, 283,920 British ancestry brown or black hair individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 3 × 10−14.

How common The G allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 11, band 11q13.1 — in an intron of OVOL1.

What each result means

G/G Two copies of the version the research linked to Blond vs. brown/black hair color. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Blond vs. brown/black hair color. That is a smaller link than two copies.
T/T No copy of the version the research linked to Blond vs. brown/black hair color. This is the starting point the study compared everyone against.
Source

Questions about rs56019505

What is rs56019505?

rs56019505 is a single position in the genome, in or near the OVOL1 gene. Published research associates it with blond vs. brown/black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs56019505 linked to?

On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.

Does having rs56019505 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs56019505 come from?

GWAS Catalog, Nature communications 2018, PMID:30531825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Blond vs. brown/black hair color (rs56019505). MyGeneLog™. https://www.mygenelog.com/variants/rs56019505

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