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Monocyte percentage of white cells variance

RAI14 · rs559732278

What the study found

Who was studied 403,135 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 2.06 higher (95% confidence interval 1.48-2.64); p = 4 × 10−12.

Where it sits Chromosome 5, band 5p13.2 — in an intron of RAI14.

What each result means

A/A Two copies of the version the research linked to Monocyte percentage of white cells variance. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Monocyte percentage of white cells variance. That is a smaller link than two copies.
G/G No copy of the version the research linked to Monocyte percentage of white cells variance. This is the starting point the study compared everyone against.
Source

Questions about rs559732278

What is rs559732278?

rs559732278 is a single position in the genome, in or near the RAI14 gene. Published research associates it with monocyte percentage of white cells variance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs559732278 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs559732278 come from?

GWAS Catalog, Nature communications 2025, PMID:40335489. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Monocyte percentage of white cells variance (rs559732278). MyGeneLog™. https://www.mygenelog.com/variants/rs559732278

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