Sensitive

Multiple sclerosis

near LRATD1 · rs559664213

Where this position leads

Condition: Multiple Sclerosis

rs559664213 Condition: Multiple Sclerosis Multiple Sclerosis Condition rs559664213 rs559664213 near LRATD1

What the study found

Who was studied 637 African American or Afro-Caribbean cases, 121,065 African American or Afro-Caribbean controls, 2,762 European ancestry cases, 447,721 European ancestry controls, 228 Hispanic or Latin American cases, 59,600 Hispanic or Latin American controls.

The effect Each copy of the C allele shifted the measure 3.42 lower (95% confidence interval 3.4-3.44); p = 2 × 10−11.

How common The C allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 2, band 2p24.3 — between genes, 83.8 kb from LRATD1.

What each result means

C/C Two copies of the version the research linked to Multiple sclerosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Multiple sclerosis. That is a smaller link than two copies.
T/T No copy of the version the research linked to Multiple sclerosis. This is the starting point the study compared everyone against.
Source

Questions about rs559664213

What is rs559664213?

rs559664213 is a single position in the genome, in or near the near LRATD1 gene. Published research associates it with multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs559664213 linked to?

On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.

Does having rs559664213 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs559664213 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Multiple sclerosis (rs559664213). MyGeneLog™. https://www.mygenelog.com/variants/rs559664213

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