Standard

Polyunsaturated fatty acids to saturated fatty acids ratio

ALDH1A2 · rs55966152

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−12, with 7 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 4 × 10−13.

Where it sits Chromosome 15, band 15q21.3 — inside ALDH1A2.

What each result means

A/A No copy of the version the research linked to Polyunsaturated fatty acids to saturated fatty acids ratio. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Polyunsaturated fatty acids to saturated fatty acids ratio. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Polyunsaturated fatty acids to saturated fatty acids ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs55966152

What is rs55966152?

rs55966152 is a single position in the genome, in or near the ALDH1A2 gene. Published research associates it with polyunsaturated fatty acids to saturated fatty acids ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs55966152 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55966152 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Polyunsaturated fatty acids to saturated fatty acids ratio (rs55966152). MyGeneLog™. https://www.mygenelog.com/variants/rs55966152

← See all variants