Standard

Estimated glomerular filtration rate

CCDC158 · rs55948430

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 10,008 Taiwanese ancestry individuals; replicated in up to 110,517 European ancestry individuals, up to 16,840 African American individuals.

The effect Each copy of the T allele shifted the measure 0.01 lower (95% confidence interval 0.008-0.012); p = 3 × 10⁻²⁵.

Where it sits Chromosome 4, band 4q21.1 — in an intron of CCDC158.

What each result means

C/C No copy of the version the research linked to Estimated glomerular filtration rate. This is the starting point the study compared everyone against.

C/T One copy of the version the research linked to Estimated glomerular filtration rate. That is a smaller link than two copies.

T/T Two copies of the version the research linked to Estimated glomerular filtration rate. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genome-Wide Association Study for eGFR in a Taiwanese Population

Chen YC, Wong HS, Wu MY, Chou WH, Kao CC, Chao CH, Chang WC, Wu MS

Clinical journal of the American Society of Nephrology : CJASN · 2022 · PMID 36223920

Questions about rs55948430

What is rs55948430?

rs55948430 is a single position in the genome, in or near the CCDC158 gene. Published research associates it with estimated glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs55948430 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55948430 come from?

GWAS Catalog, Clinical journal of the American Society of Nephrology : CJASN 2022, PMID:36223920. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Estimated glomerular filtration rate (rs55948430). MyGeneLog™. https://www.mygenelog.com/variants/rs55948430

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